Selank

Selank is a synthetic heptapeptide derived from tuftsin, an immunomodulatory peptide, and studied for anxiolytic activity without the sedation associated with benzodiazepines.

Russian studies report that Selank raises BDNF expression in the hippocampus and frontal cortex, a pathway linked to memory and mood regulation.

In rodent models, intranasal Selank protected against ethanol-induced memory impairment during withdrawal, an effect tied to normalized BDNF content in these brain regions.

This continues to drive research into its role in anxiety, cognition, and neuroplasticity.